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CyFlow™ CD28 Purified

CyFlow™ CD28 Purified
Application: Flow cytometry, Functional assays, Immunoprecipitation
Clonality: monoclonal
Regulatory Status: RUO
Source Species: Mouse
Field of Interest: Immunophenotyping, MHC
Format/Fluorochrome: Purified
Isotype: IgG1
Target Species: Rat
Antigen: CD28
Alternative Name: Tp44
Clone: JJ319
Order number: CZ432604
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ CD28 Purified"
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenMouse A20J B lymphoma cells transfected with rat CD28
Background InformationCD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. Its analog CTLA-4, expressed on the surface of activated T cells, has higher affinity to CD80 and CD86 than CD28 and downregulates T cell activity.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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