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CyFlow™ CD43 APC-Cy7
Application: | Flow cytometry |
Clonality: | monoclonal |
Target Species: | Human |
Regulatory Status: | RUO |
Source Species: | Mouse |
Field of Interest: | Immunophenotyping |
Laser: | Red |
Isotype: | IgG1 |
Format/Fluorochrome: | APC-Cy7 |
Excitation Maximum: | 650 nm, 750 nm |
Emission Maximum: | 780 nm |
Antigen: | CD43 |
Alternative Name: | Leukosialin, sialophorin |
Clone: | MEM-59 |
Order number: | CQ526140 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
HLDA Workshop HLDA IV—WS Code N 604 HLDA V—WS Code AS S290 Quantity 100 tests Volume... more
Product information "CyFlow™ CD43 APC-Cy7"
HLDA Workshop | HLDA IV—WS Code N 604 HLDA V—WS Code AS S290 |
Quantity | 100 tests |
Volume | 0.4 mL |
Immunogen | Human T lymphocytes |
Background Information | CD43 (leukosialin, sialophorin) is a transmembrane mucin-like protein with high negative charge, expressed on the surface of most hematopoietic cells. CD43 contributes to a repulsive barrier that interferes with cellular adhesion, however, in certain cases also promotes leukocyte aggregation. By interaction with actin-binding proteins ezrin and moesin, CD43 plays a regulatory role in remodeling T-cell morphology and regulates cell-cell interactions during lymphocyte traffic. CD43 signaling both enhances LFA-1 adhesiveness and counteracts LFA-1 induction via other receptors. Expression of CD43 causes induction of functionally active tumor suppressor p53 protein, but in case of p53 and ARF defficiency CD43 promotes tumour proliferation and viability. It appears to be an important modulator of leukocyte functions. |
Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
- CyFlow™ CD43 APC-Cy7 (MEM-59) CS645683 TDS US, CA EN.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) CQ526140 TDS RUO.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) CS645683 TDS ASR EN.pdf
Certificate Of Analysis
- CyFlow CD43 APC-Cy7 CS645683 COA 902827.pdf
- CyFlow CD43 APC-Cy7_CS645683_COA_901701.pdf
- CyFlow CD43 APC-Cy7 CS645683 COA 904172.pdf
- CyFlow CD43 APC-Cy7 AX148750 COA 904172.pdf
- CyFlow CD43 APC-Cy7 AX148750 COA 905611.pdf
- CyFlow CD43 APC-Cy7 CS645683 COA 905611.pdf
- CyFlow CD43 APC-Cy7 AX148750 COA 906778.pdf
- CyFlow CD43 APC-Cy7 CS645683 COA 906778.pdf
- CyFlow CD43 APC-Cy7 AX148750 COA 908496.pdf
- CyFlow CD43 APC-Cy7 CS645683 COA 908496.pdf
ECDoC
Instruction for Use
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU CZ CZ.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU DE DE.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU DK DK.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU ES ES.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU FR FR.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU GB EN.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU GR EL.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU IT IT.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU NL NL.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU NO NO.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU PL PL.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU PT PT.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU RU RU.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU SE SV.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU SK SK.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU TR TR.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU BG BG.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU HR HR.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU RO RO.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU SI SL.pdf
- CyFlow CD43 APC-Cy7 (MEM-59) AX148750 IFU RS SR.pdf
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