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CyFlow™ CD45 PE-Cy7
| Application: | Flow cytometry |
| Isotype: | IgG1 |
| Clone: | MEM-28 |
| Alternative Name: | B220, LCA, T200 |
| Antigen: | CD45 |
| Emission Maximum: | 785 nm |
| Format/Fluorochrome: | PE-Cy7 |
| Excitation Maximum: | 496 nm, 565 nm |
| Clonality: | monoclonal |
| Laser: | Blue, Green, Yellow |
| Field of Interest: | Immunophenotyping, Phosphorylation |
| Source Species: | Mouse |
| Regulatory Status: | RUO |
| Target Species: | Human |
| Order number: | BG888853 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Quantity 100 tests Volume 0.4 mL Immunogen Human thymocytes and T lymphocytes... more
Product information "CyFlow™ CD45 PE-Cy7"
| Quantity | 100 tests |
| Volume | 0.4 mL |
| Immunogen | Human thymocytes and T lymphocytes |
| Background Information | CD45 (LCA; leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing; these isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. Besides the role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. |
| Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
- CyFlow™ CD45 PE-Cy7 (2D1) CH381773 TDS US,CA EN.pdf
- CyFlow CD45 PE-Cy7 (MEM-28) BG888853 TDS RUO.pdf
- CyFlow CD45 PE-Cy7 (2D1) CH381773 TDS ASR EN.pdf
Instruction for Use
- CyFlow CD45 PE-Cy7 (2D1) AV712880 IFU CZ CZ.pdf
- CyFlow CD45 PE-Cy7 (2D1) AV712880 IFU DK DK.pdf
- CyFlow CD45 PE-Cy7 (2D1) AV712880 IFU FR FR.pdf
- CyFlow CD45 PE-Cy7 (2D1) AV712880 IFU GB EN.pdf
- CyFlow CD45 PE-Cy7 (2D1) AV712880 IFU GR EL.pdf
- CyFlow CD45 PE-Cy7 (2D1) AV712880 IFU IT IT.pdf
- CyFlow CD45 PE-Cy7 (2D1) AV712880 IFU NL NL.pdf
- CyFlow CD45 PE-Cy7 (2D1) AV712880 IFU NO NO.pdf
- CyFlow CD45 PE-Cy7 (2D1) AV712880 IFU PL PL.pdf
- CyFlow CD45 PE-Cy7 (2D1) AV712880 IFU RU RU.pdf
- CyFlow CD45 PE-Cy7 (2D1) AV712880 IFU SE SV.pdf
- CyFlow CD45 PE-Cy7 (2D1) AV712880 IFU SK SK.pdf
- CyFlow CD45 PE-Cy7 (2D1) AV712880 IFU TR TR.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU CZ CZ.pdf
- CyFlow CD45 PE-Cy7 (2D1) AV712880 IFU DE DE.pdf
- CyFlow CD45 PE-Cy7 (2D1) AV712880 IFU ES ES.pdf
- CyFlow CD45 PE-Cy7 (2D1) AV712880 IFU PT PT.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU DE DE.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU DK DK.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU ES ES.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU FR FR.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU GB EN.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU GR EL.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU IT IT.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU NL NL.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU NO NO.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU PL PL.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU PT PT.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU RU RU.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU SE SV.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU SK SK.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU TR TR.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU BG BG.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU HR HR.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU RO RO.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU SI SL.pdf
- CyFlow CD45 PE-Cy7 (2D1) CT265581 IFU RS SR.pdf
ECDoC
Certificate Of Analysis
- CyFlow CD45 PE-Cy7 AV712880 COA 902025.pdf
- CyFlow CD45 PE-Cy7 CH381773 COA 902025.pdf
- CyFlow CD45 PE-Cy7 AV712880 COA 903344.pdf
- CyFlow CD45 PE-Cy7 CH381773 COA 903344.pdf
- CyFlow CD45 PE-Cy7 CT265581 COA 904734.pdf
- CyFlow CD45 PE-Cy7 AV712880 COA 904734.pdf
- CyFlow CD45 PE-Cy7 CH381773 COA 906232.pdf
- CyFlow CD45 PE-Cy7 CT265581 COA 906232.pdf
- CyFlow CD45 PE-Cy7 CH381773 COA 908551.pdf
- CyFlow CD45 PE-Cy7 CT265581 COA 908551.pdf
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