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CyFlow™ CD45 APC-Cy7
| Application: | Flow cytometry |
| Excitation Maximum: | 650 nm, 750 nm |
| Clone: | MEM-28 |
| Alternative Name: | B220, LCA, T200 |
| Antigen: | CD45 |
| Emission Maximum: | 780 nm |
| Format/Fluorochrome: | APC-Cy7 |
| Clonality: | monoclonal |
| Isotype: | IgG1 |
| Laser: | Red |
| Field of Interest: | Immunophenotyping, Phosphorylation |
| Source Species: | Mouse |
| Regulatory Status: | RUO |
| Target Species: | Human |
| Order number: | AB648275 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Quantity 100 tests Volume 0.4 mL Immunogen Human thymocytes and T lymphocytes... more
Product information "CyFlow™ CD45 APC-Cy7"
| Quantity | 100 tests |
| Volume | 0.4 mL |
| Immunogen | Human thymocytes and T lymphocytes |
| Background Information | CD45 (LCA; leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing; these isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. Besides the role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. |
| Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
- CyFlow™ CD45 APC-Cy7 (2D1) CU144358 TDS US,CA EN.pdf
- CyFlow CD45 APC-Cy7 (MEM-28) AB648275 TDS RUO.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU144358 TDS ASR EN.pdf
Instruction for Use
- CyFlow CD45 APC-Cy7 (2D1) AY009470 IFU CZ CZ.pdf
- CyFlow CD45 APC-Cy7 (2D1) AY009470 IFU DK DK.pdf
- CyFlow CD45 APC-Cy7 (2D1) AY009470 IFU GR EL.pdf
- CyFlow CD45 APC-Cy7 (2D1) AY009470 IFU IT IT.pdf
- CyFlow CD45 APC-Cy7 (2D1) AY009470 IFU NL NL.pdf
- CyFlow CD45 APC-Cy7 (2D1) AY009470 IFU NO NO.pdf
- CyFlow CD45 APC-Cy7 (2D1) AY009470 IFU PL PL.pdf
- CyFlow CD45 APC-Cy7 (2D1) AY009470 IFU RU RU.pdf
- CyFlow CD45 APC-Cy7 (2D1) AY009470 IFU SE SV.pdf
- CyFlow CD45 APC-Cy7 (2D1) AY009470 IFU SK SK.pdf
- CyFlow CD45 APC-Cy7 (2D1) AY009470 IFU TR TR.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU CZ CZ.pdf
- CyFlow CD45 APC-Cy7 (2D1) AY009470 IFU DE DE.pdf
- CyFlow CD45 APC-Cy7 (2D1) AY009470 IFU ES ES.pdf
- CyFlow CD45 APC-Cy7 (2D1) AY009470 IFU FR FR.pdf
- CyFlow CD45 APC-Cy7 (2D1) AY009470 IFU GB EN.pdf
- CyFlow CD45 APC-Cy7 (2D1) AY009470 IFU PT PT.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU DE DE.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU DK DK.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU ES ES.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU FR FR.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU GB EN.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU GR EL.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU IT IT.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU NL NL.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU NO NO.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU PL PL.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU PT PT.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU RU RU.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU SE SV.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU SK SK.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU TR TR.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU BG BG.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU HR HR.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU RO RO.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU SI SL.pdf
- CyFlow CD45 APC-Cy7 (2D1) CU936251 IFU RS SR.pdf
ECDoC
Certificate Of Analysis
- CyFlow CD45 APC-Cy7 AY009470 COA 901956.pdf
- CyFlow CD45 APC-Cy7 CU144358 COA 901956.pdf
- CyFlow CD45 APC-Cy7 CU144358 COA 902814.pdf
- CyFlow CD45 APC-Cy7 CU144358 COA 903607.pdf
- CyFlow CD45 APC-Cy7 CU144358 COA 904502.pdf
- CyFlow CD45 APC-Cy7 CU936251 COA 904502.pdf
- CyFlow CD45 APC-Cy7 CU144358 COA 906683.pdf
- CyFlow CD45 APC-Cy7 CU936251 COA 906683.pdf
- CyFlow CD45 APC-Cy7 CU144358 COA 908350.pdf
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