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CyFlow™ CD45R0 PE-Cy7
Application: | Flow cytometry |
Excitation Maximum: | 496 nm, 565 nm |
Alternative Name: | UCHL-1 |
Antigen: | CD45R0 |
Field of Interest: | Immunophenotyping, Phosphorylation |
Isotype: | IgG2a |
Emission Maximum: | 785 nm |
Format/Fluorochrome: | PE-Cy7 |
Laser: | Blue, Green, Yellow |
Clonality: | monoclonal |
Source Species: | Mouse |
Regulatory Status: | RUO |
Target Species: | Human |
Clone: | UCHL1 |
Order number: | CS876696 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
HLDA Workshop HLDA III—WS Code NL 826 HLDA III—WS Code T 128 HLDA IV—WS Code N 31 HLDA V—WS... more
Product information "CyFlow™ CD45R0 PE-Cy7"
HLDA Workshop | HLDA III—WS Code NL 826 HLDA III—WS Code T 128 HLDA IV—WS Code N 31 HLDA V—WS Code BP BP460 HLDA V—WS Code T T-081 HLDA V—WS Code T T-CD45.43 |
Quantity | 100 tests |
Volume | 0.4 mL |
Immunogen | Human IL-2 dependent T cells |
Background Information | CD45R0 (UCHL-1) is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45R0 is expressed e.g. on macrophages, CD8+ T cells, activated T cells and myeloma cells. |
Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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