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CyFlow™ CD45RA APC
| Application: | Flow cytometry |
| Clonality: | monoclonal |
| Target Species: | Human |
| Regulatory Status: | RUO |
| Isotype: | IgG2b |
| Source Species: | Mouse |
| Field of Interest: | Immunophenotyping, Phosphorylation |
| Format/Fluorochrome: | APC |
| Laser: | Red |
| Excitation Maximum: | 650 nm |
| Emission Maximum: | 660 nm |
| Antigen: | CD45RA |
| Alternative Name: | Leu18 |
| Clone: | MEM-56 |
| Order number: | AH648116 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
HLDA Workshop HLDA IV—WS Code NL 907 Quantity 100 tests Volume 1.0 mL Immunogen... more
Product information "CyFlow™ CD45RA APC"
| HLDA Workshop | HLDA IV—WS Code NL 907 |
| Quantity | 100 tests |
| Volume | 1.0 mL |
| Immunogen | Human thymocytes and T lymphocytes |
| Background Information | CD45RA (Leu18) is a high molecular weight isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RA is expressed e.g. on naive T cells and normal plasma cells. |
| Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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