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CyFlow™ CD62P Purified

CyFlow™ CD62P Purified
Application: Flow cytometry, Functional assays, Immunocytochemistry, Immunoprecipitation, Western blot
Clonality: monoclonal
Target Species: Human, Non-Human Primates
Regulatory Status: RUO
Source Species: Mouse
Field of Interest: Immunophenotyping
Format/Fluorochrome: Purified
Isotype: IgG1
Antigen: CD62P
Alternative Name: P-selectin
Clone: AK4
Order number: AR454696
HLDA Workshop HLDA VI—WS Code P-44 Concentration Unit mg/mL Concentration 1... more
Product information "CyFlow™ CD62P Purified"
HLDA WorkshopHLDA VI—WS Code P-44
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenHuman platelets
Background InformationCD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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