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CyFlow™ CD63 Purified
| Application: | Flow cytometry, Immunocytochemistry, Immunohistochmistry (paraffin-embedded sections), Immunoprecipitation |
| Clone: | MEM-259 |
| Alternative Name: | LAMP-3, LIMP, MLA1 |
| Antigen: | CD63 |
| Isotype: | IgG1 |
| Clonality: | monoclonal |
| Format/Fluorochrome: | Purified |
| Field of Interest: | Endocytosis, Immunophenotyping |
| Source Species: | Mouse |
| Regulatory Status: | RUO |
| Target Species: | Human |
| Order number: | BA410547 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ CD63 Purified"
| Concentration Unit | mg/mL |
| Concentration | 1 |
| Quantity | 0.1 mg |
| Volume | 0.1 mL |
| Immunogen | Human Acute Lymphocytic Leukemia (ALL) T cells |
| Background Information | CD63 (LAMP-3; lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. It is also present in the plasma membrane, usually following cell activation. Hence, it has become an widely used basophil activation marker. In mast cells, however, CD63 exposition does not need their activation. CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell costimulation molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas. |
| Storage Buffer | The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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