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CyFlow™ CD72 PE
| Application: | Flow cytometry |
| Laser: | Blue, Green, Yellow |
| Alternative Name: | Lyb-2, LYB2 |
| Antigen: | CD72 |
| Emission Maximum: | 576 nm |
| Excitation Maximum: | 496 nm, 565 nm |
| Format/Fluorochrome: | PE |
| Clonality: | monoclonal |
| Field of Interest: | Immunophenotyping |
| Source Species: | Mouse |
| Isotype: | IgG2b |
| Regulatory Status: | RUO |
| Target Species: | Human |
| Clone: | 3F3 |
| Order number: | AA664263 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Quantity 100 tests Volume 2.0 mL Immunogen Normal human lymphocytes from lymph node... more
Product information "CyFlow™ CD72 PE"
| Quantity | 100 tests |
| Volume | 2.0 mL |
| Immunogen | Normal human lymphocytes from lymph node |
| Background Information | CD72 is a transmembrane glycoprotein expressed as a homodimer especially in B cells, but also in other antigen presenting cells such as dendritic cells and macrophages. Through one of its immunoreceptor tyrosine-based inhibitory motives (ITIMs), CD72 interacts with tyrosine phosphatase SHP-1, thereby suppressing B cell responsiveness. Binding of CD72 with its ligand CD100 (Sema4D) prevents BCR association and phosphorylation of CD72 and results in dissociation of SHP-1 from CD72, thus enables B cell activation. |
| Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 20·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests. |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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