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CyFlow™ CD79a APC
Application: | Flow cytometry |
Target Species: | Chicken, Cow, Dog, Guinea pig, Horse, Human, Mouse, Non-Human Primates, Pig, Rabbit, Rat |
Alternative Name: | IgA, MB-1, MB1 |
Antigen: | CD79a |
Clonality: | monoclonal |
Isotype: | IgG1 |
Emission Maximum: | 660 nm |
Excitation Maximum: | 650 nm |
Laser: | Red |
Format/Fluorochrome: | APC |
Field of Interest: | Immunophenotyping |
Source Species: | Mouse |
Regulatory Status: | RUO |
Clone: | HM47 |
Order number: | AQ406223 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Quantity 100 tests Volume 1.0 mL Immunogen Synthetic peptide corresponding to C... more
Product information "CyFlow™ CD79a APC"
Quantity | 100 tests |
Volume | 1.0 mL |
Immunogen | Synthetic peptide corresponding to C terminal amino acids 208-222 of human CD79a |
Background Information | CD79a (Ig α, MB1) forms disulfide-linked heterodimer with CD79b (Ig β, B29). They both are transmembrane proteins with extended cytoplasmic domains containing immunoreceptor tyrosine activation motives (ITAMs), and together with cell surface immunoglobulin they constitute B-cell antigen-specific receptor (BCR). CD79a and b are the first components of BCR that are expressed developmentally. They appear on pro-B cells in association with the endoplasmic reticulum chaperone calnexin. Subsequently, in pre-B cells, CD79 heterodimer is associated with λ5-VpreB surrogate immunoglobulin and later with antigen-specific surface immunoglobulins. At the plasma cell stage, CD79a is present as an intracellular component. CD79a/b complex interacts with Src-family tyrosine kinase Lyn, which phosphorylates its cytoplasmic ITAM motives to form docking sites for downstream signaling. |
Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
- CyFlow™ CD79a APC (HM57) BL177563 TDS US,CA EN.pdf
- CyFlow CD79a APC (HM47) AQ406223 TDS RUO.pdf
- CyFlow CD79a APC (HM57) AJ298129 TDS RUO.pdf
- CyFlow CD79a APC (HM57) BL177563 TDS ASR EN.pdf
Instruction for Use
- CyFlow CD79a APC (HM57) BK592023 IFU CZ CZ.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU CZ CZ.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU DE DE.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU DK DK.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU ES ES.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU FR FR.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU GB EN.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU GR EL.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU IT IT.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU NL NL.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU NO NO.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU PL PL.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU PT PT.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU RU RU.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU SE SV.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU SK SK.pdf
- CyFlow CD79a APC (HM57) CZ033810 IFU TR TR.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU DE DE.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU DK DK.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU ES ES.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU FR FR.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU GB EN.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU GR EL.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU IT IT.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU NL NL.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU NO NO.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU PL PL.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU PT PT.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU RU RU.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU SE SV.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU SK SK.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU TR TR.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU BG BG.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU HR HR.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU RO RO.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU SI SL.pdf
- CyFlow CD79a APC (HM57) BK592023 IFU RS SR.pdf
ECDoC
Certificate Of Analysis
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