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CyFlow™ CD79a FITC
Application: | Flow cytometry |
Target Species: | Chicken, Cow, Guinea pig, Horse, Human, Mouse, Opossum, Pig, Rabbit, Rat |
Clone: | HM57 |
Alternative Name: | IgA, MB-1, MB1 |
Antigen: | CD79a |
Clonality: | monoclonal |
Isotype: | IgG1 |
Field of Interest: | Immunophenotyping |
Source Species: | Mouse |
Emission Maximum: | 518 nm |
Excitation Maximum: | 490 to 495 nm |
Laser: | Blue |
Regulatory Status: | RUO |
Format/Fluorochrome: | FITC |
Order number: | CV675949 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
HLDA Workshop HLDA V—WS Code BC cB018 HLDA VI—WS Code BP 193 HLDA VI—WS Code BP 89 HLDA VI—WS... more
Product information "CyFlow™ CD79a FITC"
HLDA Workshop | HLDA V—WS Code BC cB018 HLDA VI—WS Code BP 193 HLDA VI—WS Code BP 89 HLDA VI—WS Code B B103 HLDA VI—WS Code B CD79.4 |
Quantity | 100 tests |
Volume | 0.4 mL |
Immunogen | Synthetic peptide corresponding to amino acids 202-216 of human CD79a |
Background Information | CD79a (Ig α, MB1) forms disulfide-linked heterodimer with CD79b (Ig β, B29). They both are transmembrane proteins with extended cytoplasmic domains containing immunoreceptor tyrosine activation motives (ITAMs), and together with cell surface immunoglobulin they constitute B-cell antigen-specific receptor (BCR). CD79a and b are the first components of BCR that are expressed developmentally. They appear on pro-B cells in association with the endoplasmic reticulum chaperone calnexin. Subsequently, in pre-B cells, CD79 heterodimer is associated with λ5-VpreB surrogate immunoglobulin and later with antigen-specific surface immunoglobulins. At the plasma cell stage, CD79a is present as an intracellular component. CD79a/b complex interacts with Src-family tyrosine kinase Lyn, which phosphorylates its cytoplasmic ITAM motives to form docking sites for downstream signaling. |
Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
Certificate Of Analysis
- CyFlow CD79a FITC AD255544 COA 901910.pdf
- CyFlow CD79a FITC AD255544 COA 903720.pdf
- CyFlow CD79a FITC AZ161577 COA 904574.pdf
- CyFlow CD79a FITC AD255544 COA 904574.pdf
- CyFlow CD79a FITC AD255544 COA 907825.pdf
ECDoC
Instruction for Use
- CyFlow CD79a FITC (HM57) AZ161577 IFU CZ CZ.pdf
- CyFlow CD79a FITC (HM57) AZ161577 IFU DE DE.pdf
- CyFlow CD79a FITC (HM57) AZ161577 IFU DK DK.pdf
- CyFlow CD79a FITC (HM57) AZ161577 IFU ES ES.pdf
- CyFlow CD79a FITC (HM57) AZ161577 IFU FR FR.pdf
- CyFlow CD79a FITC (HM57) AZ161577 IFU GR EL.pdf
- CyFlow CD79a FITC (HM57) AZ161577 IFU IT IT.pdf
- CyFlow CD79a FITC (HM57) AZ161577 IFU NL NL.pdf
- CyFlow CD79a FITC (HM57) AZ161577 IFU NO NO.pdf
- CyFlow CD79a FITC (HM57) AZ161577 IFU PL PL.pdf
- CyFlow CD79a FITC (HM57) AZ161577 IFU PT PT.pdf
- CyFlow CD79a FITC (HM57) AZ161577 IFU RU RU.pdf
- CyFlow CD79a FITC (HM57) AZ161577 IFU SE SV.pdf
- CyFlow CD79a FITC (HM57) AZ161577 IFU SK SK.pdf
- CyFlow CD79a FITC (HM57) AZ161577 IFU TR TR.pdf
- CyFlow CD79a FITC (HM57) AZ161577 IFU GB EN.pdf
- CyFlow CD79a FITC (HM57) AZ161577 IFU BG BG.pdf
- CyFlow CD79a FITC (HM57) AZ161577 IFU HR HR.pdf
- CyFlow CD79a FITC (HM57) AZ161577 IFU RO RO.pdf
- CyFlow CD79a FITC (HM57) AZ161577 IFU SI SL.pdf
- CyFlow CD79a FITC (HM57) AZ161577 IFU RS SR.pdf
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