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CyFlow™ CD88 PE
| Application: | Flow cytometry |
| Excitation Maximum: | 496 nm, 565 nm |
| Clone: | S5/1 |
| Alternative Name: | C5aR |
| Antigen: | CD88 |
| Target Species: | Cow, Ferret, Human, Rabbit |
| Isotype: | IgG2a |
| Emission Maximum: | 576 nm |
| Laser: | Blue, Green, Yellow |
| Clonality: | monoclonal |
| Format/Fluorochrome: | PE |
| Field of Interest: | Immunophenotyping |
| Source Species: | Mouse |
| Regulatory Status: | RUO |
| Order number: | AH752120 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Quantity 100 tests Volume 1.0 mL Immunogen Recombinant N-terminal peptide... more
Product information "CyFlow™ CD88 PE"
| Quantity | 100 tests |
| Volume | 1.0 mL |
| Immunogen | Recombinant N-terminal peptide (Asp15-Asp27) of human C5aR |
| Background Information | CD88 (C5aR) is a G protein-coupled seven membrane-spanning protein serving as a receptor for C5a component of the complement cascade, and is expressed mainly by monocytes, macrophages, neutrophils, eosinophils, and mast cells, but also e.g. by hepatocytes, glial cells, vascular endothelial cells, or cardiomyocytes. The binding of C5a to CD88 is associated with inflammatory response, including superoxide anion production, chemotaxis, and increased production of acute phase proteins. Expression of CD88 on synovial mast cells and their C5a-mediated degranulation plays a role in pathogenesis of rheumatoid arthritis. |
| Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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