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CyFlow™ CD105 Alexa Fluor™ 488
| Application: | Flow cytometry |
| Clonality: | monoclonal |
| Target Species: | Human, Rat |
| Regulatory Status: | RUO |
| Laser: | Blue |
| Source Species: | Mouse |
| Field of Interest: | Immunophenotyping |
| Isotype: | IgG2a |
| Format/Fluorochrome: | Alexa Fluor™ 488 |
| Excitation Maximum: | 495 nm |
| Emission Maximum: | 519 nm |
| Antigen: | CD105 |
| Alternative Name: | Endoglin |
| Clone: | MEM-226 |
| Order number: | BM597424 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Quantity 100 tests Volume 0.4 mL Immunogen Recombinant Vaccinia virus containing the... more
Product information "CyFlow™ CD105 Alexa Fluor™ 488"
| Quantity | 100 tests |
| Volume | 0.4 mL |
| Immunogen | Recombinant Vaccinia virus containing the human CD105 cDNA |
| Background Information | CD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFβR-2 as a receptor for TGFβ-1 and TGFβ-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonizes the inhibitory effects of TGFβ-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels. |
| Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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