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CyFlow™ CD105 Purified

CyFlow™ CD105 Purified
Application: Flow cytometry, Immunohistochemistry (frozen sections), Immunoprecipitation, Western blot
Clonality: monoclonal
Regulatory Status: RUO
Field of Interest: Immunophenotyping, MHC
Format/Fluorochrome: Purified
Isotype: IgG2a
Target Species: Mouse
Source Species: Rat
Antigen: CD105
Alternative Name: Endoglin
Clone: MJ7/18
Order number: AP974049
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ CD105 Purified"
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenInflamed mouse skin
Background InformationCD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFβR-2 as a receptor for TGFβ-1 and TGFβ-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonizes the inhibitory effects of TGFβ-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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