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CyFlow™ CD112 PE
Application: | Flow cytometry |
Excitation Maximum: | 496 nm, 565 nm |
Alternative Name: | HVEB, Hve B, Nectin-2, PRR2 |
Antigen: | CD112 |
Isotype: | IgG1 |
Emission Maximum: | 576 nm |
Laser: | Blue, Green, Yellow |
Clonality: | monoclonal |
Format/Fluorochrome: | PE |
Field of Interest: | Immunophenotyping |
Source Species: | Mouse |
Regulatory Status: | RUO |
Target Species: | Human |
Clone: | R2.525 |
Order number: | AL095410 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Quantity 100 tests Volume 1.0 mL Immunogen Not available Background Information... more
Product information "CyFlow™ CD112 PE"
Quantity | 100 tests |
Volume | 1.0 mL |
Immunogen | Not available |
Background Information | CD112 (nectin-2) is a transmembrane glycoprotein involved in organization of adherens junctions. It also serves as a target molecule for entry of certain strains of herpes simplex virus (HSV) and pseudorabies virus (PRV). It is homologous to CD155, which serves as a target molecule for polio virus. CD112 seems to play a role in neural tube formation, with N-cadherin. Inside the cell, CD112 is connected with actin cytoskeleton through afadin. Variations in the CD112 gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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