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CyFlow™ CD123 PE-Cy7
Application: | Flow cytometry |
Isotype: | IgG1 |
Alternative Name: | IL-3Ra, IL3R |
Antigen: | CD123 |
Field of Interest: | Immunophenotyping, Signaling |
Emission Maximum: | 785 nm |
Format/Fluorochrome: | PE-Cy7 |
Excitation Maximum: | 496 nm, 565 nm |
Clonality: | monoclonal |
Laser: | Blue, Green, Yellow |
Source Species: | Mouse |
Regulatory Status: | RUO |
Target Species: | Human |
Clone: | 6H6 |
Order number: | BF349525 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Quantity 100 tests Volume 0.4 mL Immunogen IL3 receptor α chain expressed on the... more
Product information "CyFlow™ CD123 PE-Cy7"
Quantity | 100 tests |
Volume | 0.4 mL |
Immunogen | IL3 receptor α chain expressed on the surface of transiently transfected COS cells |
Background Information | CD123 is the α chain of interleukin 3 receptor (IL-3R α). This subunit heterodimerizes with the interleukin 3 receptor β chain (CD131), which is shared with other receptors. CD123 interacts with IL-3 specifically, but with low affinity, and association with the β subunit confers high affinity binding to the receptor heterodimer. Both chains are required for signaling, but receptor activation and signal transduction depend on IL-3 binding to CD123 as the initial step. |
Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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