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CyFlow™ CD123 Purified

CyFlow™ CD123 Purified
Application: Flow cytometry, Immunohistochemistry (frozen sections), Immunoprecipitation, Western blot
Clonality: monoclonal
Target Species: Human
Regulatory Status: RUO
Source Species: Mouse
Field of Interest: Immunophenotyping, Signaling
Format/Fluorochrome: Purified
Isotype: IgG1
Antigen: CD123
Alternative Name: IL-3Ra, IL3R
Clone: 6H6
Order number: CL344110
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ CD123 Purified"
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenIL3 receptor α chain expressed on the surface of transiently transfected COS cells
Background InformationCD123 is the α chain of interleukin 3 receptor (IL-3R α). This subunit heterodimerizes with the interleukin 3 receptor β chain (CD131), which is shared with other receptors. CD123 interacts with IL-3 specifically, but with low affinity, and association with the β subunit confers high affinity binding to the receptor heterodimer. Both chains are required for signaling, but receptor activation and signal transduction depend on IL-3 binding to CD123 as the initial step.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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