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CyFlow™ CD129 PE

CyFlow™ CD129 PE
Application: Flow cytometry
Laser: Blue, Green, Yellow
Alternative Name: IL-9Ra, IL9R
Antigen: CD129
Field of Interest: Immunophenotyping, Signaling
Emission Maximum: 576 nm
Excitation Maximum: 496 nm, 565 nm
Clonality: monoclonal
Format/Fluorochrome: PE
Source Species: Mouse
Isotype: IgG2b
Regulatory Status: RUO
Target Species: Human
Clone: AH9R7
Order number: CE042379
Quantity 100 tests Volume 1.0 mL Immunogen Human CD129-transfected cells... more
Product information "CyFlow™ CD129 PE"
Quantity100 tests
Volume1.0 mL
ImmunogenHuman CD129-transfected cells
Background InformationCD129 serves as the high affinity α subunit of IL-9 receptor (IL-9R α). It associates with CD132, the common γ chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.
UsageThe reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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