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CyFlow™ CD137 PE
| Application: | Flow cytometry |
| Excitation Maximum: | 496 nm, 565 nm |
| Alternative Name: | 4-1BB, TNFRSF9 |
| Antigen: | CD137 |
| Target Species: | Human, Non-Human Primates |
| Isotype: | IgG1 |
| Emission Maximum: | 576 nm |
| Laser: | Blue, Green, Yellow |
| Clonality: | monoclonal |
| Format/Fluorochrome: | PE |
| Field of Interest: | Immunophenotyping |
| Source Species: | Mouse |
| Regulatory Status: | RUO |
| Clone: | 4B4-1 |
| Order number: | BN858229 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Quantity 100 tests Volume 1.0 mL Immunogen Recombinant human CD137 ectodomain... more
Product information "CyFlow™ CD137 PE"
| Quantity | 100 tests |
| Volume | 1.0 mL |
| Immunogen | Recombinant human CD137 ectodomain |
| Background Information | CD137 (TNFRSF9, 4-1BB), is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival. Soluble forms of CD137 may provide negative control mechanism for some immune responses. |
| Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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