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CyFlow™ CD140a Biotin
Application: | Flow cytometry |
Clonality: | monoclonal |
Target Species: | Human |
Regulatory Status: | RUO |
Source Species: | Mouse |
Field of Interest: | Immunophenotyping, Signaling |
Isotype: | IgG1 |
Format/Fluorochrome: | Biotin |
Antigen: | CD140a |
Alternative Name: | PDGFRA, PDGRF2 |
Clone: | 16A1 |
Order number: | AS196282 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ CD140a Biotin"
Concentration Unit | mg/mL |
Concentration | 1 |
Quantity | 0.1 mg |
Volume | 0.1 mL |
Immunogen | CD140a-transfected NIH 3T3 cells |
Background Information | CD140a (PDGF-RA; platelet-derived growth factor receptor α) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140a forms homodimers, or heterodimerizes with CD140b (PDGF-RB). Whereas CD140b induces in different cell types their proliferation and migration, the role of CD140a is more controversial, with pro-proliferative or anti-proliferative effects. CD140a has early developmental functions, mediates mesodermal cell migration, and later acts in signaling associated in epithelial-mesenchymal interactions. |
Usage | The reagent is designed for indirect immunofluorescence analysis by Flow Cytometry. Suggested working usage is 3·µg/ml. Indicated dilution is recommended starting point for use of this product, but working concentrations should be validated by the investigator. |
Storage Buffer | The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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