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CyFlow™ CD152 PE
Application: | Flow cytometry |
Laser: | Blue, Green, Yellow |
Alternative Name: | CTLA-4, CTL Ag 4 |
Antigen: | CD152 |
Isotype: | IgG2a |
Emission Maximum: | 576 nm |
Excitation Maximum: | 496 nm, 565 nm |
Clonality: | monoclonal |
Format/Fluorochrome: | PE |
Field of Interest: | Immunophenotyping |
Source Species: | Mouse |
Regulatory Status: | RUO |
Target Species: | Human |
Clone: | BNI3 |
Order number: | CV021049 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Quantity 100 tests Volume 1.0 mL Immunogen Human CD152-IgG heavy chain fusion protein... more
Product information "CyFlow™ CD152 PE"
Quantity | 100 tests |
Volume | 1.0 mL |
Immunogen | Human CD152-IgG heavy chain fusion protein |
Background Information | CD152 (CTLA-4) is a homodimeric transmembrane protein similar to CD28 and binding the same ligands, i.e. CD80 (B7.1) and CD86 (B7.2), but with higher affinity. Unlike CD28 with important costimulating functions, CD152 acts as an important inhibitory receptor essential for modulation of the immune system. CD152 becomes transiently expressed on activated T cells and its malfunction can cause autoimmune diseases, such as insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, or thyroid-associated orbitopathy. |
Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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