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CyFlow™ CD154 Purified

CyFlow™ CD154 Purified
Application: Flow cytometry, Functional assays, Immunocytochemistry
Alternative Name: CD40L, gp39, IMD3, T-BAM, TNFSF5, TRAP-1
Antigen: CD154
Target Species: Human, Non-Human Primates
Clonality: monoclonal
Isotype: IgG1
Format/Fluorochrome: Purified
Field of Interest: Immunophenotyping
Source Species: Mouse
Regulatory Status: RUO
Clone: 24-31
Order number: CZ459497
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ CD154 Purified"
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenHuman CD154 fusion protein
Background InformationCD154 / CD40L (CD40 ligand) is a member of the tumor necrosis factor family, and is expressed primarily on activated CD4+ lymphocytes, but also on mast cells, basophils, eosinophils and human dendritic cells. Its counter-receptor CD40 is expressed on antigen presenting cells, including dendritic cells, macrophages, and B cells, and also on fibroblasts. Triggering of CD40 by CD40L causes maturation of dendritic cells and upregulation of antigen presentation in functions of the MHC and costimulatory molecules. CD40L also functions as a direct stimulating factor for T cells. CD40L plays also roles e.g. in antibody class switching and modulation of apoptosis in the germinal center.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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