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CyFlow™ CD161 Purified
| Application: | Flow cytometry, Immunohistochemistry (frozen sections), Immunoprecipitation, Radioimmunoassay, Western blot |
| Alternative Name: | NKR, NKR-P1A, NKRP1A |
| Antigen: | CD161 |
| Target Species: | Rat |
| Clonality: | monoclonal |
| Field of Interest: | Immunophenotyping, MHC |
| Isotype: | IgG1 |
| Format/Fluorochrome: | Purified |
| Source Species: | Mouse |
| Regulatory Status: | RUO |
| Clone: | 10/78 |
| Order number: | BG633525 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ CD161 Purified"
| Concentration Unit | mg/mL |
| Concentration | 1 |
| Quantity | 0.1 mg |
| Volume | 0.1 mL |
| Immunogen | Splenic cells purified from the LEW rat |
| Background Information | CD161 (Nkrp1; natural killer receptor protein 1 or Klrb1; killer cell lectin-like receptor subfamily b member 1) is a disulphide-linked homodimeric receptor, which is involved in regulation of NK cell and NKT cell function. It is expressed on rat NK cells, subset of T cells, dendritic cells, and activated monocytes. Although human CD161 is expressed as one isoform, the rat CD161 has three isoforms, referred to as CD161a, b, and c. These proteins contain C-terminal C-type lectin extracellular domain, a transmembrane domain, and N-terminal intracellular domain, which contains ITIM motif, such as CD161b, and displays inhibitory function, or does not contain ITIM motif, thus also not the inhibitory function, such as CD161a. |
| Storage Buffer | The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
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