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CyFlow™ CD161 PE
| Application: | Flow cytometry |
| Excitation Maximum: | 496 nm, 565 nm |
| Alternative Name: | NKR, NKR-P1A, NKRP1A |
| Antigen: | CD161 |
| Target Species: | Human, Non-Human Primates |
| Isotype: | IgG1 |
| Emission Maximum: | 576 nm |
| Laser: | Blue, Green, Yellow |
| Clonality: | monoclonal |
| Format/Fluorochrome: | PE |
| Field of Interest: | Immunophenotyping |
| Source Species: | Mouse |
| Regulatory Status: | RUO |
| Clone: | HP-3G10 |
| Order number: | AY505662 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Quantity 100 tests Volume 1.0 mL Immunogen Human NK cells Background Information... more
Product information "CyFlow™ CD161 PE"
| Quantity | 100 tests |
| Volume | 1.0 mL |
| Immunogen | Human NK cells |
| Background Information | CD161 (Nkrp1; natural killer receptor protein 1 or Klrb1; killer cell lectin-like receptor subfamily b member 1) is a disulphide-linked homodimeric receptor, which is involved in regulation of NK cell and NKT cell function. It is expressed on rat NK cells, subset of T cells, dendritic cells, and activated monocytes. Although human CD161 is expressed as one isoform, the rat CD161 has three isoforms, referred to as CD161a, b, and c. These proteins contain C-terminal C-type lectin extracellular domain, a transmembrane domain, and N-terminal intracellular domain, which contains ITIM motif, such as CD161b, and displays inhibitory function, or does not contain ITIM motif, thus also not the inhibitory function, such as CD161a. |
| Usage | The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
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