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CyFlow™ CD177 Purified

CyFlow™ CD177 Purified
Application: Flow cytometry, Immunoprecipitation, Western blot
Alternative Name: HNA-2a, HNA2A, NB-1, NB1, PRV1
Antigen: CD177
Target Species: Human, Non-Human Primates
Clonality: monoclonal
Isotype: IgG1
Format/Fluorochrome: Purified
Field of Interest: Immunophenotyping
Source Species: Mouse
Regulatory Status: RUO
Clone: MEM-166
Order number: BF539640
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ CD177 Purified"
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenHuman granulocytes
Background InformationCD177 (NB1, HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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