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CyFlow™ CD178 PE

CyFlow™ CD178 PE
Application: Flow cytometry
Isotype: IgG1
Alternative Name: APO-1L, APT1LG, CD95-L, CD95L, Fas-L, FAS-Ligand, TNFSF6 ligand
Antigen: CD178
Field of Interest: Apoptosis, Immunophenotyping
Emission Maximum: 576 nm
Clonality: monoclonal
Excitation Maximum: 496 nm, 565 nm
Laser: Blue, Green, Yellow
Format/Fluorochrome: PE
Source Species: Mouse
Regulatory Status: RUO
Target Species: Human
Clone: NOK-1
Order number: BZ157747
Quantity 100 tests Volume 1.0 mL Immunogen L5178Y mouse T lymphoma cells expressing... more
Product information "CyFlow™ CD178 PE"
Quantity100 tests
Volume1.0 mL
ImmunogenL5178Y mouse T lymphoma cells expressing recombinant human CD178
Background InformationCD178 (Fas-L; Fas ligand or CD95L), a member of TNF family transmembrane glycoproteins, is responsible for induction of apoptosis in cells containing its receptor Fas/CD95. The CD178-mediated apoptosis pathway has been implicated in peripheral tolerance, tissue pathology, and maintenance of the immune privileged sites. Defects in this interaction may be related to some cases of systemic lupus erythematosus (SLE). CD178 was also described as a co-stimulatory receptor for T-cell activation in mice in vivo.
UsageThe reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide and 0.2% (w/v) BSA.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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