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CyFlow™ CD253 Low Endotoxin

CyFlow™ CD253 Low Endotoxin
Application: Flow cytometry, Functional assays
Field of Interest: Apoptosis, Immunophenotyping
Alternative Name: Apo-2L, Apo2L, TNF-Related Apoptosis Inducing Ligand, TNFSF10, TRAIL
Antigen: CD253
Format/Fluorochrome: Low Endotoxin
Clonality: monoclonal
Isotype: IgG1
Source Species: Mouse
Regulatory Status: RUO
Target Species: Human
Clone: 2E5
Order number: AM151429
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ CD253 Low Endotoxin"
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenRecombinant soluble fragment (aa 95-281) of human TRAIL
Background InformationCD253 (TRAIL; TNF-Related Apoptosis Inducing Ligand or Apo2) is a type II membrane protein from the TNF family. TRAIL is a cytotoxic protein which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL-induced apotosis, is achieved through binding to two dealth-signaling receptors, DR4 (CD261 / TRAIL-R1) and DR5 (CD262 / TRAIL-R2).
Storage BufferThe reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
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