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CyFlow™ CD264 PE
| Application: | Flow cytometry |
| Emission Maximum: | 576 nm |
| Alternative Name: | DCR2, TNFRSF10d, TRAILR4, TRUNDD |
| Antigen: | CD264 |
| Field of Interest: | Apoptosis, Immunophenotyping |
| Isotype: | IgG1 |
| Excitation Maximum: | 496 nm, 565 nm |
| Clonality: | monoclonal |
| Laser: | Blue, Green, Yellow |
| Format/Fluorochrome: | PE |
| Source Species: | Mouse |
| Regulatory Status: | RUO |
| Target Species: | Human |
| Clone: | TRAIL-R4-01 |
| Order number: | CY292936 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Concentration Unit mg/mL Concentration 0,1 Quantity 0.1 mg Volume 1.0 mL... more
Product information "CyFlow™ CD264 PE"
| Concentration Unit | mg/mL |
| Concentration | 0,1 |
| Quantity | 0.1 mg |
| Volume | 1.0 mL |
| Immunogen | TRAIL-R4 (aa 1-210) - hIgGhc fusion protein |
| Background Information | CD264 (TRAIL-R4, TR4, DcR2, TRUNDD), expressed mainly on CD8+ and NK cells, belongs to receptors of TRAIL, a TNF-like membrane toxic protein that induces apoptosis in many tumor cells, but not in normal cells. TRAIL-R4, however, contains partially truncated death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by impairment death-inducing signaling complex (DISC) processing. TRAIL-R4 interacts with death receptor 5 (DR5) in the native DISC in a TRAIL-dependent manner and prevents its corecruitment with death receptor 4 (DR4). |
| Usage | The reagent is designed for Flow Cytometry analysis. Suggested working usage is 3·µg/ml. Indicated dilution is recommended starting point for use of this product, but working concentrations should be validated by the investigator. |
| Storage Buffer | The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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