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CyFlow™ LARGE1 Purified
| Application: | Flow cytometry, Western blot |
| Clonality: | monoclonal |
| Target Species: | Human |
| Regulatory Status: | RUO |
| Isotype: | IgG2b |
| Source Species: | Mouse |
| Format/Fluorochrome: | Purified |
| Field of Interest: | Others |
| Antigen: | LARGE1 |
| Clone: | LARGE-02 |
| Order number: | AF160681 |
For Research Use Only
Not for use in diagnostic or therapeutic procedures.
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ LARGE1 Purified"
| Concentration Unit | mg/mL |
| Concentration | 1 |
| Quantity | 0.1 mg |
| Volume | 0.1 mL |
| Immunogen | Recombinant fragment of human LARGE1 (amino acids 35-142) |
| Background Information | LARGE1 serves as a glycosyltransferase which participates in glycosylation of the muscle membrane protein α-dystroglycan. Mutations of LARGE1 lead to hypoglycosylation of α-dystroglycan and cause congenital muscular dystrophy (MDC1D) associated with severe mental retardation. Altered α-dystroglycan glycosylation may also play a role in cancer, as hypoglycosylation of the protein and loss of laminin binding have been demonstrated in invasive carcinoma cells. |
| Storage Buffer | The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide. |
| Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
| Stability | Do not use after expiration date stamped on vial label. |
Safety Data Sheet
Technical Data Sheet
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