Welcome to
Sysmex Flow Cytometry Other European Country!

For ordering please make sure you are in your local shop.
If you are from Other European Country then please continue.
Otherwise please go to your country.

Go to my country Continue

Article successfully added.

CyFlow™ Lck Alexa Fluor™ 647

CyFlow™ Lck Alexa Fluor™ 647
Application: Flow cytometry
Clonality: monoclonal
Target Species: Human
Regulatory Status: RUO
Source Species: Mouse
Laser: Red
Excitation Maximum: 650 nm
Isotype: IgG1
Format/Fluorochrome: Alexa Fluor™ 647
Emission Maximum: 665 nm
Field of Interest: Phosphorylation
Antigen: Lck
Clone: LCK-01
Order number: BG039735
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
Product information "CyFlow™ Lck Alexa Fluor™ 647"
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenPeptide corresponding to amino acids 22-36 in the sequence of human Lck
Background InformationLck is a Src-family tyrosine kinase, which is essential for signaling through the T-cell receptor (TCR) complex. Upon TCR triggering, Lck phosphorylates the ITAM motives in its ζ subunits, establishing binding sites for the SH2 domains of the tyrosine kinase ZAP70, which is also phosphorylated by Lck and thereby activated to generate subsequent signaling platforms by phosphorylation of adaptor LAT. Whereas the majority of Lck is localized to the plasma membrane, there is also a significant fraction associated with the Golgi apparatus, which may contribute to Raf activation under conditions of weak stimulation through the TCR. Lck is also involved in the regulation of apoptosis induced by various stimuli, but not by the death receptors.
UsageThe reagent is designed for Flow Cytometry analysis. Suggested working usage is 5·µg/ml. Indicated dilution is recommended starting point for use of this product, but working concentrations should be validated by the investigator.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
Similar products
FITC
CyFlow™ CD1a FITC
Antigen: CD1a
Clone: SK9
Application: Flow cytometry
Regulatory Status: RUO
Target Species: Human
Quantity: 100 tests
PE
CyFlow™ CD1a PE
Antigen: CD1a
Clone: SK9
Application: Flow cytometry
Regulatory Status: RUO
Target Species: Human
Quantity: 100 tests
APC
CyFlow™ CD1a APC
Antigen: CD1a
Clone: SK9
Application: Flow cytometry
Regulatory Status: RUO
Target Species: Human
Quantity: 100 tests
Purified
CyFlow™ CD1a Purified
Antigen: CD1a
Clone: SK9
Application: Flow cytometry, Immunoprecipitation
Regulatory Status: RUO
Target Species: Human
Quantity: 0.1 mg
FITC
CyFlow™ CD1b FITC
Antigen: CD1b
Clone: SN13
Application: Flow cytometry
Regulatory Status: RUO
Target Species: Human
Quantity: 100 tests
Purified
CyFlow™ CD1b Purified
Antigen: CD1b
Clone: SN13
Application: Flow cytometry, Immunohistochemistry, Immunoprecipitation
Regulatory Status: RUO
Target Species: Human
Quantity: 0.1 mg
PE
CyFlow™ CD1c PE
Antigen: CD1c
Clone: L161
Application: Flow cytometry
Regulatory Status: RUO
Target Species: Human
Quantity: 100 tests
Purified
CyFlow™ CD1c Purified
Antigen: CD1c
Clone: L161
Application: Flow cytometry, Immunohistochemistry, Immunoprecipitation
Regulatory Status: RUO
Target Species: Human
Quantity: 0.1 mg

 

Need more information?
Need more information?
Service Hotline | Contact | Benefits
Service hotline
tel: +49 (40) 527 26 0 Mon-Fri, 9 am - 5 pm

Contact
Use our contact form